Dendritic Cells from Crohn’s Disease Patients Show Aberrant STAT1 and STAT3 Signaling

Abnormalities of dendritic cells (DCs) and STAT proteins have been reported in Crohn’s disease (CD). Studies on JAK/STAT signaling in DCs are, however, lacking in CD. We applied a flowcytometric single-cell-based phosphoepitope assay to evaluate STAT1 and STAT3 pathways in DC subsets from CD patient...

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Detalhes bibliográficos
Main Authors: Nieminen, Janne K., Niemi, Mirja, Sipponen, Taina, Salo, Harri M., Klemetti, Paula, Färkkilä, Martti, Vakkila, Jukka, Vaarala, Outi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737363/
https://ncbi.nlm.nih.gov/pubmed/23950992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070738
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