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Functional Stoichiometry Underlying KChIP Regulation of Kv4.2 Functional Expression

KChIPs enhance functional expression of Kv4 channels by binding to an N-terminal regulatory region located in the first 40 amino acids of Kv4.2 that we call the Functional Expression Regulating N-terminal (FERN) domain. Mutating two residues in the FERN domain to alanines, W8A and F11A, disrupts KCh...

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Detalhes bibliográficos
Main Authors: Kunjilwar, Kumud, Qian, Yan, Pfaffinger, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737270/
https://ncbi.nlm.nih.gov/pubmed/23692269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12309
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