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Integrin alpha(2)beta(1) (α(2)β(1)) Promotes Prostate Cancer Skeletal Metastasis

Men who die of prostate cancer (PCa) do so because of systemic metastases, the most frequent of which are within the skeleton. Recent data suggest that the colonization of the skeleton is mediated in part by collagen type I, the most abundant protein within the bone. We have shown that enhanced coll...

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Detalhes bibliográficos
Main Authors: Sottnik, Joseph L., Daignault-Newton, Stephanie, Zhang, Xiaotun, Morrissey, Colm, Hussain, Maha H., Keller, Evan T., Hall, Christopher L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736758/
https://ncbi.nlm.nih.gov/pubmed/23242739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10585-012-9561-6
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