Slit2 Prevents Neutrophil Recruitment and Renal Ischemia-Reperfusion Injury

Neutrophils recruited to the postischemic kidney contribute to the pathogenesis of ischemia-reperfusion injury (IRI), which is the most common cause of renal failure among hospitalized patients. The Slit family of secreted proteins inhibits chemotaxis of leukocytes by preventing activation of Rho-fa...

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Hlavní autoři: Chaturvedi, Swasti, Yuen, Darren A., Bajwa, Amandeep, Huang, Yi-Wei, Sokollik, Christiane, Huang, Liping, Lam, Grace Y., Tole, Soumitra, Liu, Guang-Ying, Pan, Jerry, Chan, Lauren, Sokolskyy, Yaro, Puthia, Manoj, Godaly, Gabriela, John, Rohan, Wang, Changsen, Lee, Warren L., Brumell, John H., Okusa, Mark D., Robinson, Lisa A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Nephrology 2013
Témata:
Basic Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736708/
https://ncbi.nlm.nih.gov/pubmed/23766538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012090890
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