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Ratiometric Imaging of the T-Cell Actin Cytoskeleton Reveals the Nature of Receptor-Induced Cytoskeletal Enrichment

The T-cell actin cytoskeleton mediates adaptive immune system responses to peptide antigens by physically directing the motion and clustering of T-cell receptors (TCRs) on the cell surface. When TCR movement is impeded by externally applied physical barriers, the actin network exhibits transient enr...

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Bibliographic Details
Main Authors: Smoligovets, Alexander A., Smith, Adam W., Groves, Jay T.
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736690/
https://ncbi.nlm.nih.gov/pubmed/23931330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.06.031
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