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Characterization of dynamic actin associations with T-cell receptor microclusters in primary T cells

T cell triggering through T-cell antigen receptors (TCRs) results in spatial assembly of the receptors on multiple length scales. This assembly is mediated by the T cell actin cytoskeleton, which reorganizes in response to TCR phosphorylation and then induces the coalescence of TCRs into microcluste...

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Detalhes bibliográficos
Main Authors: Smoligovets, Alexander A., Smith, Adam W., Wu, Hung-Jen, Petit, Rebecca S., Groves, Jay T.
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367833/
https://ncbi.nlm.nih.gov/pubmed/22389407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.092825
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