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Apical domain polarization localizes actin-myosin activity to drive ratchet-like apical constriction

Apical constriction promotes epithelia folding, which changes tissue architecture. During Drosophila gastrulation, mesoderm cells exhibit repeated contractile pulses that are stabilized such that cells apically constrict like a ratchet. The transcription factor Twist is required to stabilize cell sh...

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Detalles Bibliográficos
Main Authors: Mason, Frank M., Tworoger, Michael, Martin, Adam C.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736338/
https://ncbi.nlm.nih.gov/pubmed/23831726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2796
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