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Peripherally Induced Tregs – Role in Immune Homeostasis and Autoimmunity

Thymically derived Foxp3(+) regulatory T cells (tTregs) constitute a unique T cell lineage that is essential for maintaining immune tolerance to self and immune homeostasis. However, Foxp3 can also be turned on in conventional T cells as a consequence of antigen exposure in the periphery, under both...

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Bibliografiske detaljer
Main Authors: Yadav, Mahesh, Stephan, Stephen, Bluestone, Jeffrey A.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736167/
https://ncbi.nlm.nih.gov/pubmed/23966994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00232
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