RDH10, RALDH2, and CRABP2 are required components of PPARγ-directed ATRA synthesis and signaling in human dendritic cells

All-trans retinoic acid (ATRA) has a key role in dendritic cells (DCs) and affects T cell subtype specification and gut homing. However, the identity of the permissive cell types and the required steps of conversion of vitamin A to biologically active ATRA bringing about retinoic acid receptor-regul...

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Hlavní autoři: Gyöngyösi, Adrienn, Szatmari, Istvan, Pap, Attila, Dezső, Balazs, Pos, Zoltan, Széles, Lajos, Varga, Tamas, Nagy, Laszlo
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Biochemistry and Molecular Biology 2013
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735943/
https://ncbi.nlm.nih.gov/pubmed/23833249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M038984
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