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Identification of Known and Novel PTCH Mutations in Both Syndromic and Non-syndromic Keratocystic Odontogenic Tumors

AIM: To clarify the role of PTCH in patients with NBCCS-related and non-sydromic keratocystic odontogenic tumors. METHODOLOGY: Mutation analysis was undertaken in 8 sporadic and 4 NBCCS-associated KCOTs. RESULTS: Four novel and two known mutations were identified in 2 sporadic and 3 syndromic cases,...

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Detalhes bibliográficos
Main Authors: Pan, Shuang, Xu, Li-li, Sun, Li-sha, Li, Tie-jun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735790/
https://ncbi.nlm.nih.gov/pubmed/20690502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4248/ijos.08013
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