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Intermittent injections of osteocalcin reverse autophagic dysfunction and endoplasmic reticulum stress resulting from diet-induced obesity in the vascular tissue via the NFκB-p65-dependent mechanism

The osteoblast-specific secreted molecule osteocalcin behaves as a hormone-regulating glucose and lipid metabolism, but the role of osteocalcin in cardiovascular disease (CVD) is not fully understood. In the present study, we investigated the effect of osteocalcin on autophagy and endoplasmic reticu...

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Bibliografische gegevens
Hoofdauteurs: Zhou, Bo, Li, Huixia, Liu, Jiali, Xu, Lin, Zang, Weijin, Wu, Shufang, Sun, Hongzhi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Landes Bioscience 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735704/
https://ncbi.nlm.nih.gov/pubmed/23708521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.24929
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