Hypoxia-Ischemia or Excitotoxin-Induced Tissue Plasminogen Activator- Dependent Gelatinase Activation in Mice Neonate Brain Microvessels

Hypoxia-ischemia (HI) and excitotoxicity are validated causes of neonatal brain injuries and tissue plasminogen activator (t-PA) participates in the processes through proteolytic and receptor-mediated pathways. Brain microvascular endothelial cells from neonates in culture, contain and release more...

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Autors principals: Omouendze, Priscilla L., Henry, Vincent J., Porte, Baptiste, Dupré, Nicolas, Carmeliet, Peter, Gonzalez, Bruno J., Marret, Stéphane, Leroux, Philippe
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735506/
https://ncbi.nlm.nih.gov/pubmed/23940734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071263
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