Mechanism of enhanced oral absorption of hydrophilic drug incorporated in hydrophobic nanoparticles

Hydroxysafflor yellow A (HSYA) is an effective ingredient of the Chinese herb Carthamus tinctorius L, which has high water solubility and low oral bioavailability. This research aims to develop a hydrophobic nanoparticle that can enhance the oral absorption of HSYA. Transmission electron microscopy...

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Bibliographic Details
Main Authors: Lv, Liang-Zhong, Tong, Chen-Qi, Yu, Jia, Han, Min, Gao, Jian-Qing
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2013
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735274/
https://ncbi.nlm.nih.gov/pubmed/23935363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S47400
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