Identification of new genetic risk factors for prostate cancer

There is evidence that a substantial part of genetic predisposition to prostate cancer (PCa) may be due to lower penetrance genes which are found by genome-wide association studies. We have recently conducted such a study and seven new regions of the genome linked to PCa risk have been identified. T...

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Main Authors: Guy, Michelle, Kote-Jarai, Zsofia, Giles, Graham G., Al Olama, Ali Amin, Jugurnauth, Sarah K., Mulholland, Shani, Leongamornlert, Daniel A., Edwards, Stephen M., Morrison, Jonathan, Field, Helen I., Southey, Melissa C., Severi, Gianluca, Donovan, Jenny L., Hamdy, Freddie C., Dearnaley, David P., Muir, Kenneth R., Smith, Charmaine, Bagnato, Melisa, Ardern-Jones, Audrey T., Hall, Amanda L., O'Brien, Lynne T., Gehr-Swain, Beatrice N., Wilkinson, Rosemary A., Cox, Angela, Lewis, Sarah, Brown, Paul M., Jhavar, Sameer G., Tymrakiewicz, Malgorzata, Lophatananon, Artitaya, Bryant, Sarah L., Horwich, Alan, Huddart, Robert A., Khoo, Vincent S., Parker, Christopher C., Woodhouse, Christopher J., Thompson, Alan, Christmas, Tim, Ogden, Chris, Fisher, Cyril, Jameson, Charles, Cooper, Colin S., English, Dallas R., Hopper, John L., Neal, David E., Easton, Douglas F., Eeles, Rosalind A.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2009
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735221/
https://ncbi.nlm.nih.gov/pubmed/19050691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aja.2008.18
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