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Amniotic fluid stem cell-based models to study the effects of gene mutations and toxicants on male germ cell formation

Male infertility is a major public health issue predominantly caused by defects in germ cell development. In the past, studies on the genetic regulation of spermatogenesis as well as on negative environmental impacts have been hampered by the fact that human germ cell development is intractable to d...

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Main Authors: Gundacker, Claudia, Dolznig, Helmut, Mikula, Mario, Rosner, Margit, Brandau, Oliver, Hengstschläger, Markus
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735087/
https://ncbi.nlm.nih.gov/pubmed/22231297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aja.2011.170
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