Manganese superoxide dismutase promotes anoikis resistance and tumor metastasis

Normal cells require adhesion to extracellular matrix for survival. Cell detachment causes a drastic increase in reactive oxygen species (ROS) that promotes anoikis. In the present study, we observed that upon detachment from matrix, human mammary epithelial cells strongly upregulate manganese super...

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Detalhes bibliográficos
Main Authors: Kamarajugadda, S, Cai, Q, Chen, H, Nayak, S, Zhu, J, He, M, Jin, Y, Zhang, Y, Ai, L, Martin, S S, Tan, M, Lu, J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734828/
https://ncbi.nlm.nih.gov/pubmed/23429290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.20
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