AMP kinase activation and glut4 translocation in isolated cardiomyocytes

SUMMARY: Activation of AMP-activated protein kinase (AMPK) results in glucose transporter 4 (GLUT4) translocation from the cytosol to the cell membrane, and glucose uptake in the skeletal muscles. This increased activation of AMPK can be stimulated by a pharmacological agent, AICAR (5’-aminoimidazol...

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Main Authors: Webster, Ingrid, Friedrich, Sven O, Lochner, Amanda, Huisamen, Barbara
Format: Artigo
Jezik:Inglês
Izdano: Clinics Cardive Publishing 2010
Teme:
Cardiovascular Topics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734761/
https://ncbi.nlm.nih.gov/pubmed/20532430
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