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The mechanical uncoupler blebbistatin is associated with significant electrophysiological effects in the isolated rabbit heart

Blebbistatin (BS) is a recently discovered inhibitor of the myosin II isoform and has been adopted as the mechanical uncoupler of choice for optical mapping, because previous studies suggest that BS has no significant cardiac electrophysiological effects in a number of species. The aim of this study...

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Hlavní autoři: Brack, Kieran E, Narang, Ravi, Winter, James, Ng, G André
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734628/
https://ncbi.nlm.nih.gov/pubmed/23291912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/expphysiol.2012.069369
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