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Protective and Pathogenic Roles for B Cells During Systemic Autoimmunity in NZB/W F(1) Mice()

Delineating the relative contributions of B lymphocytes during the course of autoimmune disease has been difficult. Therefore, the effects of depleting all mature B cells using a potent CD20 mAb, or depleting circulating and marginal zone B cells using a ligand-blocking CD22 mAb were compared in NZB...

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Detalhes bibliográficos
Main Authors: Haas, Karen M., Watanabe, Rei, Matsushita, Takashi, Nakashima, Hiroko, Ishiura, Nobuko, Okochi, Hitoshi, Fujimoto, Manabu, Tedder, Thomas F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734557/
https://ncbi.nlm.nih.gov/pubmed/20368280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902391
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