Aromatic L-Amino Acid Decarboxylase (AADC) Is Crucial for Brain Development and Motor Functions

Aromatic L-amino acid decarboxylase (AADC) deficiency is a rare pediatric neuro-metabolic disease in children. Due to the lack of an animal model, its pathogenetic mechanism is poorly understood. To study the role of AADC in brain development, a zebrafish model of AADC deficiency was generated. We i...

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Bibliografski detalji
Glavni autori: Shih, De-Fen, Hsiao, Chung-Der, Min, Ming-Yuan, Lai, Wen-Sung, Yang, Chianne-Wen, Lee, Wang-Tso, Lee, Shyh-Jye
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734303/
https://ncbi.nlm.nih.gov/pubmed/23940784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071741
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