Pirfenidone Nanoparticles Improve Corneal Wound Healing and Prevent Scarring Following Alkali Burn

PURPOSE: To evaluate the effects of pirfenidone nanoparticles on corneal re-epithelialization and scarring, major clinical challenges after alkali burn. METHODS: Effect of pirfenidone on collagen I and α-smooth muscle actin (α-SMA) synthesis by TGFβ induced primary corneal fibroblast cells was evalu...

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Bibliografiske detaljer
Main Authors: Chowdhury, Sushovan, Guha, Rajdeep, Trivedi, Ruchit, Kompella, Uday B., Konar, Aditya, Hazra, Sarbani
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734236/
https://ncbi.nlm.nih.gov/pubmed/23940587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070528
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