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Translesion synthesis of acetylaminofluorene-dG adducts by DNA polymerase ζ is stimulated by yeast Rev1 protein

Translesion synthesis is an important mechanism in response to unrepaired DNA lesions during replication. The DNA polymerase ζ (Polζ) mutagenesis pathway is a major error-prone translesion synthesis mechanism requiring Polζ and Rev1. In addition to its dCMP transferase, a non-catalytic function of R...

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Main Authors: Guo, Dongyu, Xie, Zhongwen, Shen, Huiyun, Zhao, Bo, Wang, Zhigang
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2004
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC373411/
https://ncbi.nlm.nih.gov/pubmed/14960722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh279
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