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An integrated hierarchical Bayesian approach to normalizing left-censored microRNA microarray data

BACKGROUND: MicroRNAs (miRNAs) are small endogenous ssRNAs that regulate target gene expression post-transcriptionally through the RNAi pathway. A critical pre-processing procedure for detecting differentially expressed miRNAs is normalization, aiming at removing the between-array systematic bias. M...

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Bibliografische gegevens
Hoofdauteurs: Kang, Jia, Xu, Ethan Yixun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734108/
https://ncbi.nlm.nih.gov/pubmed/23885888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-14-507
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