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Mutually dependent degradation of Ama1p and Cdc20p terminates APC/C ubiquitin ligase activity at the completion of meiotic development in yeast
BACKGROUND: The execution of meiotic nuclear divisions in S. cerevisiae is regulated by protein degradation mediated by the anaphase promoting complex/cyclosome (APC/C) ubiquitin ligase. The correct timing of APC/C activity is essential for normal chromosome segregation. During meiosis, the APC/C is...
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Formato: | Artigo |
Idioma: | Inglês |
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BioMed Central
2013
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3734102/ https://ncbi.nlm.nih.gov/pubmed/23816140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1747-1028-8-9 |
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