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Low Levels of Aflatoxin B1, Ricin, and Milk Enhance Recombinant Protein Production in Mammalian Cells

Gene expression in transduced mammalian cells correlates with virus titer, but high doses of vector for gene therapy leads to toxicity in humans and in animals. Changing the optimal tissue culture medium by adding low levels of environmental stressors, such as 1 µM of the fungal toxin aflatoxin B1 (...

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Bibliografische gegevens
Hoofdauteurs: Rasooly, Reuven, Hernlem, Bradley, Friedman, Mendel
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733960/
https://ncbi.nlm.nih.gov/pubmed/23940780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071682
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