Distinct single cell signal transduction signatures in leukocyte subsets stimulated with khat extract, amphetamine-like cathinone, cathine or norephedrine

BACKGROUND: Amphetamine and amphetamine derivatives are suggested to induce an immunosuppressive effect. However, knowledge of how amphetamines modulate intracellular signaling pathways in cells of the immune system is limited. We have studied phosphorylation of signal transduction proteins (Akt, CR...

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Detalhes bibliográficos
Main Authors: Bredholt, Therese, Ersvær, Elisabeth, Erikstein, Bjarte Skoe, Sulen, André, Reikvam, Håkon, Aarstad, Hans Jørgen, Johannessen, Anne Christine, Vintermyr, Olav Karsten, Bruserud, Øystein, Gjertsen, Bjørn Tore
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733921/
https://ncbi.nlm.nih.gov/pubmed/23845085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2050-6511-14-35
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