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Leptin administered in physiological or pharmacological doses does not regulate circulating angiogenesis factors in humans

AIM/HYPOTHESIS: Leptin has been shown to regulate angiogenesis in animal and in vitro studies by upregulating the production of several pro-angiogenic factors, but its role in regulating angiogenesis has never been studied in humans. METHODS: The potential angiogenic effect of two doses of metrelept...

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Autori principali: Aronis, K. N., Diakopoulos, K. N., Fiorenza, C. G., Chamberland, J. P., Mantzoros, C. S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733553/
https://ncbi.nlm.nih.gov/pubmed/21660636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-011-2201-x
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