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Recognition of DNA substrates by T4 bacteriophage polynucleotide kinase

T4 phage polynucleotide kinase (PNK) displays 5′-hydroxyl kinase, 3′-phosphatase and 2′,3′-cyclic phosphodiesterase activities. The enzyme phosphorylates the 5′ hydroxyl termini of a wide variety of nucleic acid substrates, a behavior studied here through the determination of a series of crystal str...

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Autori principali: Eastberg, Jennifer H., Pelletier, John, Stoddard, Barry L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC373337/
https://ncbi.nlm.nih.gov/pubmed/14754987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh212
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