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Stereoselective excision of thymine glycol from oxidatively damaged DNA

DNA damage created by reactive oxygen species includes the prototypic oxidized pyrimidine, thymine glycol (Tg), which exists in oxidatively damaged DNA as two diastereoisomeric pairs. In Escherichia coli, Saccharomyces cerevesiae and mice, Tg is preferentially excised by endonuclease III (Endo III)...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Principais autores: Miller, Holly, Fernandes, Andrea S., Zaika, Elena, McTigue, Monica M., Torres, M. Cecilia, Wente, Maryann, Iden, Charles R., Grollman, Arthur P.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2004
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Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC373299/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14726482/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkh190
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