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Reconstituting pancreas development from purified progenitor cells reveals genes essential for islet differentiation

Developmental biology is challenged to reveal the function of numerous candidate genes implicated by recent genome-scale studies as regulators of organ development and diseases. Recapitulating organogenesis from purified progenitor cells that can be genetically manipulated would provide powerful opp...

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Hlavní autoři: Sugiyama, Takuya, Benitez, Cecil M., Ghodasara, Amar, Liu, Lucy, McLean, Graeme W., Lee, Jonghyeob, Blauwkamp, Timothy A., Nusse, Roeland, Wright, Christopher V. E., Gu, Guoqiang, Kim, Seung K.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3732989/
https://ncbi.nlm.nih.gov/pubmed/23852729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1304507110
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