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Distinct roles of STAT3 and STAT5 in the pathogenesis and targeted therapy of breast cancer

The transcription factors STAT3 and STAT5 play important roles in the regulation of mammary gland function during pregnancy, lactation, and involution. Given that STAT3 and STAT5 regulate genes involved in proliferation and survival, it is not surprising that inappropriate activation of STAT3 and ST...

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Hlavní autoři: Walker, Sarah R., Xiang, Michael, Frank, David A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3732813/
https://ncbi.nlm.nih.gov/pubmed/23531638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2013.03.010
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