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Rapid dendritic cell activation and resistance to allotolerance induction in anti-CD154-treated mice receiving CD47-deficient donor-specific transfusion

CD47-SIRPα signaling plays an important role in regulating macrophage and dendritic cell (DC) activation. Here, we investigated the role of CD47 expression on donor cells in tolerance induction by combined treatment with donor-specific transfusion (DST) plus anti-CD154 mAb in a mouse model of fully...

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Detalhes bibliográficos
Main Authors: Wang, Yuantao, Wang, Hui, Bronson, Roderick, Fu, Yaowen, Yang, Yong-Guang
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3732805/
https://ncbi.nlm.nih.gov/pubmed/23295133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/096368912X661346
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