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Multicomponent Synthesis of Diverse 1,4-Benzodiazepine Scaffolds

[Image: see text] The 1,4-benzodiazepine (BDZ) scaffold is of particular interest in drug design due to a balanced ensemble of beneficial physicochemical properties including a semi-rigid and compact diazepine ring with spatial placements of several substituents, combined with low number of rotatabl...

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Hlavní autoři: Huang, Yijun, Khoury, Kareem, Chanas, Tyler, Dömling, Alexander
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3732779/
https://ncbi.nlm.nih.gov/pubmed/23157402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol302837h
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