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“Ultra-high resolution optical trap with single fluorophore sensitivity”
We present a single-molecule instrument that combines a timeshared ultra-high resolution dual optical trap interlaced with a confocal fluorescence microscope. In a demonstration experiment, individual single-fluorophore labeled DNA oligonucleotides were observed to bind and unbind to complementary D...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3732480/ https://ncbi.nlm.nih.gov/pubmed/21336286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1574 |
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