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Contribution of Acid Sphingomyelinase in the Periaqueductal Gray Region to Morphine-induced Analgesia in Mice

Opioids are the most widely used drugs for long-term pain management, but their use is limited by the development of antinociceptive tolerance. The present study investigated the role of ceramide production via acid sphingomyelinase (ASM) activation in the periaqueductal gray region, a brain region...

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Bibliografski detalji
Glavni autori: Ritter, Joseph K., Fang, Youwen, Xia, Min, Li, Pin-Lan, Dewey, William L.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3732375/
https://ncbi.nlm.nih.gov/pubmed/22825003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WNR.0b013e3283571757
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