Nuclear Translocation of B-Cell-Specific Transcription Factor, BACH2, Modulates ROS Mediated Cytotoxic Responses in Mantle Cell Lymphoma

BACH2, a B-cell specific transcription factor, plays a critical role in oxidative stress-mediated apoptosis. Bortezomib (Velcade(TM)) is widely used to treat relapsed mantle cell lymphoma (MCL) patients despite varying clinical outcomes. As one of the potential mechanisms of action, bortezomib was r...

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Detalhes bibliográficos
Main Authors: Chen, Zheng, Pittman, Eric F., Romaguera, Jorge, Fayad, Luis, Wang, Michael, Neelapu, Sattva S., Mclaughlin, Peter, Kwak, Larry, McCarty, Nami
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3732253/
https://ncbi.nlm.nih.gov/pubmed/23936317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069126
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