Effect of the combination of metformin and fenofibrate on glucose homeostasis in diabetic Goto-Kakizaki rats

Metformin has been reported to increase the expression of the glucagon-like peptide-1 (GLP-1) receptor in pancreatic beta cells in a peroxisome proliferator-activated receptor (PPAR)-α-dependent manner. We investigated whether a PPARα agonist, fenofibrate, exhibits an additive or synergistic effect...

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Autors principals: Oh, Tae Jung, Shin, Ji Yon, Kang, Gyeong Hoon, Park, Kyong Soo, Cho, Young Min
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2013
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731660/
https://ncbi.nlm.nih.gov/pubmed/23827952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2013.58
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