Role of CTLA4 in the Proliferation and Survival of Chronic Lymphocytic Leukemia

Earlier, we reported that CTLA4 expression is inversely correlated with CD38 expression in chronic lymphocytic leukemia (CLL) cells. However, the specific role of CTLA4 in CLL pathogenesis remains unknown. Therefore, to elucidate the possible role of CTLA4 in CLL pathogenesis, CTLA4 was down-regulat...

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Main Authors: Mittal, Amit K., Chaturvedi, Nagendra K., Rohlfsen, Rae A., Gupta, Payal, Joshi, Avadhut D., Hegde, Ganapati V., Bociek, R. Gregory, Joshi, Shantaram S.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731360/
https://ncbi.nlm.nih.gov/pubmed/23936412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070352
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