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HIV-1 Envelope Glycoprotein Variable Loops Are Indispensable for Envelope Structural Integrity and Virus Entry

HIV-1 envelope (Env) glycoprotein is a trimer of heterodimer of gp120 and gp41, and derives from a trimeric glycoprotein precursor, gp160. Gp120 contains five conserved regions that are interspersed with 5 variable loop regions (V1–V5). Env variations in variable loop length and amino acid compositi...

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Detalhes bibliográficos
Main Authors: Yuan, Tingting, Li, Jingjing, Zhang, Mei-Yun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731308/
https://ncbi.nlm.nih.gov/pubmed/23936354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069789
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