The PI3K/Akt/mTOR Pathway Is Implicated in the Premature Senescence of Primary Human Endothelial Cells Exposed to Chronic Radiation

The etiology of radiation-induced cardiovascular disease (CVD) after chronic exposure to low doses of ionizing radiation is only marginally understood. We have previously shown that a chronic low-dose rate exposure (4.1 mGy/h) causes human umbilical vein endothelial cells (HUVECs) to prematurely sen...

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Main Authors: Yentrapalli, Ramesh, Azimzadeh, Omid, Sriharshan, Arundhathi, Malinowsky, Katharina, Merl, Juliane, Wojcik, Andrzej, Harms-Ringdahl, Mats, Atkinson, Michael J., Becker, Karl-Friedrich, Haghdoost, Siamak, Tapio, Soile
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731291/
https://ncbi.nlm.nih.gov/pubmed/23936371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070024
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