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Quantifying Cell Fate Decisions for Differentiation and Reprogramming of a Human Stem Cell Network: Landscape and Biological Paths

Cellular reprogramming has been recently intensively studied experimentally. We developed a global potential landscape and kinetic path framework to explore a human stem cell developmental network composed of 52 genes. We uncovered the underlying landscape for the stem cell network with two basins o...

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Detalhes bibliográficos
Main Authors: Li, Chunhe, Wang, Jin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731225/
https://ncbi.nlm.nih.gov/pubmed/23935477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003165
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