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5/6th Nephrectomy in Combination with High Salt Diet and Nitric Oxide Synthase Inhibition to Induce Chronic Kidney Disease in the Lewis Rat

Chronic kidney disease (CKD) is a global problem. Slowing CKD progression is a major health priority. Since CKD is characterized by complex derangements of homeostasis, integrative animal models are necessary to study development and progression of CKD. To study development of CKD and novel therapeu...

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Главные авторы: van Koppen, Arianne, Verhaar, Marianne C., Bongartz, Lennart G., Joles, Jaap A.
Формат: Artigo
Язык:Inglês
Опубликовано: MyJove Corporation 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731201/
https://ncbi.nlm.nih.gov/pubmed/23851420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/50398
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