C3a receptor antagonist attenuates brain injury after intracerebral hemorrhage

Neuroprotective therapy targeting the complement cascade may reduce injury associated with intracerebral hemorrhage (ICH). We investigated the role of C3a-receptor antagonist (C3aRA) after ICH in mice. Autologous whole blood was infused into the right striatum of mice that were treated with C3aRA or...

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Détails bibliographiques
Auteurs principaux: Rynkowski, Michal A, Kim, Grace H, Garrett, Matthew C, Zacharia, Brad E, Otten, Marc L, Sosunov, Sergei A, Komotar, Ricardo J, Hassid, Benjamin G, Ducruet, Andrew F, Lambris, John D, Connolly, E Sander
Format: Artigo
Langue:Inglês
Publié: 2008
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731073/
https://ncbi.nlm.nih.gov/pubmed/18728680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2008.95
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