PTX3 genetic variation and dizygotic twinning in The Gambia: could pleiotropy with innate immunity explain common dizygotic twinning in Africa?

Dizygotic (DZ) twinning has a genetic component and is common among sub-Saharan Africans; in The Gambia its frequency is up to 3% of live births. Variation in Pentraxin 3 (PTX3), a soluble pattern recognition receptor that plays an important role both in humoral innate immunity and in female fertili...

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Autori principali: Sirugo, Giorgio, Velez Edwards, Digna R., Ryckman, Kelli K., Bisseye, Cyrille, White, Marquitta J., Kebbeh, Bunja, Morris, Gerard A. J., Adegbola, Richard A., Tacconelli, Alessandra, Predazzi, Irene, Novelli, Giuseppe, Vannberg, Fredrik O., Odunsi, Kunle, Page, Grier P., Williams, Scott M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731069/
https://ncbi.nlm.nih.gov/pubmed/22834944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-1809.2012.00723.x
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