Safety and activity of crizotinib for paediatric patients with refractory solid tumours or anaplastic large-cell lymphoma: a Children’s Oncology Group phase 1 consortium study

BACKGROUND: Various human cancers have ALK gene translocations, amplifications, or oncogenic mutations, such as anaplastic large-cell lymphoma, inflammatory myofibroblastic tumours, non-small-cell lung cancer (NSCLC), and neuroblastoma. Therefore, ALK inhibition could be a useful therapeutic strateg...

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Bibliografiske detaljer
Main Authors: Mossé, Yael P, Lim, Megan S, Voss, Stephan D, Wilner, Keith, Ruffner, Katherine, Laliberte, Julie, Rolland, Delphine, Balis, Frank M, Maris, John M, Weigel, Brenda J, Ingle, Ashish M, Ahern, Charlotte, Adamson, Peter C, Blaney, Susan M
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3730818/
https://ncbi.nlm.nih.gov/pubmed/23598171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1470-2045(13)70095-0
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