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The nature of dopamine dysfunction in schizophrenia and what this means for treatment
CONTEXT: Current drug treatments for schizophrenia are inadequate for many patients and, despite five decades of drug discovery, all use the same mechanism-dopamine D2 receptor blockade. Understanding the pathophysiology of the disorder is thus likely to be critical to the rational development of ne...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3730746/ https://ncbi.nlm.nih.gov/pubmed/22474070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archgenpsychiatry.2012.169 |
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