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Nanosecond Pulsed Electric Field Stimulation of Reactive Oxygen Species in Human Pancreatic Cancer Cells is Ca(2+)-Dependent

The cellular response to 100 ns pulsed electric fields (nsPEF) exposure includes the formation of transient nanopores in the plasma membrane and organelle membranes, an immediate increase in intracellular Ca(2+), an increase in reactive oxygen species (ROS), DNA fragmentation and caspase activation....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Nuccitelli, Richard, Lui, Kaying, Kreis, Mark, Athos, Brian, Nuccitelli, Pamela
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3730523/
https://ncbi.nlm.nih.gov/pubmed/23680664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.05.014
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