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Integrin α5β1, the Fibronectin Receptor, as a Pertinent Therapeutic Target in Solid Tumors

Integrins are transmembrane heterodimeric proteins sensing the cell microenvironment and modulating numerous signalling pathways. Changes in integrin expression between normal and tumoral cells support involvement of specific integrins in tumor progression and aggressiveness. This review highlights...

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Hlavní autoři: Schaffner, Florence, Ray, Anne Marie, Dontenwill, Monique
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3730317/
https://ncbi.nlm.nih.gov/pubmed/24216697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers5010027
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