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Monoclonal antibody humanness score and its applications

BACKGROUND: Monoclonal antibody therapeutics are rapidly gaining in popularity for the treatment of a myriad of diseases, ranging from cancer to autoimmune diseases and neurological diseases. Multiple forms of antibody therapeutics are in use today that differ in the amount of human sequence present...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gao, Sean H, Huang, Kexin, Tu, Hua, Adler, Adam S
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729710/
https://ncbi.nlm.nih.gov/pubmed/23826749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-13-55
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