HIV DNA Reservoir Increases Risk for Cognitive Disorders in cART-Naïve Patients

OBJECTIVES: Cognitive impairment remains frequent in HIV, despite combination antiretroviral therapy (cART). Leading theories implicate peripheral monocyte HIV DNA reservoirs as a mechanism for spread of the virus to the brain. These reservoirs remain present despite cART. The objective of this stud...

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Hauptverfasser: Valcour, Victor G., Ananworanich, Jintanat, Agsalda, Melissa, Sailasuta, Napapon, Chalermchai, Thep, Schuetz, Alexandra, Shikuma, Cecilia, Liang, Chin-Yuan, Jirajariyavej, Supunee, Sithinamsuwan, Pasiri, Tipsuk, Somporn, Clifford, David B., Paul, Robert, Fletcher, James L. K., Marovich, Mary A., Slike, Bonnie M., DeGruttola, Victor, Shiramizu, Bruce
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729685/
https://ncbi.nlm.nih.gov/pubmed/23936155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070164
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